Agent skill · research science · aiskillstore
clinpgx-database
Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.
Why this skill is useful
Provides domain-specific knowledge on pharmacogenomics and gene-drug interactions that the AI wouldn't reliably generate on its own.
What it needs
Requires requests installed locally. About 9k tokens when loaded. Last updated 2026-08-07. 405 stars on the source repository.
What this skill does
ClinPGx Database Overview ClinPGx (Clinical Pharmacogenomics Database) is a comprehensive resource for clinical pharmacogenomics information, successor to PharmGKB. It consolidates data from PharmGKB, CPIC, and PharmCAT, providing curated information on how genetic variation affects medication response. Access gene-drug pairs, clinical guidelines, allele functions, and drug labels for precision medicine applications. When to Use This Skill This skill should be used when: Gene-drug interactions: Querying how genetic variants affect drug metabolism, efficacy, or toxicity CPIC guidelines: Accessing evidence-based clinical practice guidelines for pharmacogenetics Allele information: Retrieving allele function, frequency, and phenotype data Drug labels: Exploring FDA and other regulatory pharmacogenomic drug labeling Pharmacogenomic annotations: Accessing curated literature on gene-drug-disease relationships Clinical decision support: Using PharmDOG tool for phenoconversion and custom genotype interpretation Precision medicine: Implementing pharmacogenomic testing in clinical practice Drug metabolism: Understanding CYP450 and other pharmacogene functions Personalized dosing: Finding genotype-guided dosing recommendations Adverse drug reactions: Identifying genetic risk factors for drug toxicity Installation and Setup Python API Access The ClinPGx REST API provides programmatic access to all database resources. Basic setup: API Endpoint Rate Limits: 2 requests per second maximum Excessive requests will result in HTTP 429 (Too Many Requests) response Authentication: Not required for basic access Data License: Creative Commons Attribution-ShareAlike 4.0 International License For substantial API use, notify the ClinPGx team at api@clinpgx.org Core Capabilities 1. …
How to use it
Reference it in AdaL, Claude Code, Cursor or any coding agent — nothing to install:
@skills aiskillstore/clinpgx-database--a9148f