Agent skill · research science · aiskillstore
clinpgx-database
Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.
Why this skill is useful
Provides specific API commands and domain knowledge for accessing pharmacogenomic data that the AI wouldn't reliably generate on its own.
What it needs
Requires requests installed locally. About 9k tokens when loaded. Last updated 2026-08-07. 405 stars on the source repository.
What this skill does
ClinPGx Database Overview ClinPGx (Clinical Pharmacogenomics Database) is a comprehensive resource for clinical pharmacogenomics information, successor to PharmGKB. It consolidates data from PharmGKB, CPIC, and PharmCAT, providing curated information on how genetic variation affects medication response. Access gene-drug pairs, clinical guidelines, allele functions, and drug labels for precision medicine applications. When to Use This Skill This skill should be used when: Gene-drug interactions: Querying how genetic variants affect drug metabolism, efficacy, or toxicity CPIC guidelines: Accessing evidence-based clinical practice guidelines for pharmacogenetics Allele information: Retrieving allele function, frequency, and phenotype data Drug labels: Exploring FDA and other regulatory pharmacogenomic drug labeling Pharmacogenomic annotations: Accessing curated literature on gene-drug-disease relationships Clinical decision support: Using PharmDOG tool for phenoconversion and custom genotype interpretation Precision medicine: Implementing pharmacogenomic testing in clinical practice Drug metabolism: Understanding CYP450 and other pharmacogene functions Personalized dosing: Finding genotype-guided dosing recommendations Adverse drug reactions: Identifying genetic risk factors for drug toxicity Installation and Setup Python API Access The ClinPGx REST API provides programmatic access to all database resources. Basic setup: API Endpoint Rate Limits: 2 requests per second maximum Excessive requests will result in HTTP 429 (Too Many Requests) response Authentication: Not required for basic access Data License: Creative Commons Attribution-ShareAlike 4.0 International License For substantial API use, notify the ClinPGx team at api@clinpgx.org Core Capabilities 1. …
How to use it
Reference it in AdaL, Claude Code, Cursor or any coding agent — nothing to install:
@skills aiskillstore/clinpgx-database