Agent skill · research science · aiskillstore

brenda-database

Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.

Why this skill is useful

Adds executable scripts for querying the BRENDA enzyme database via SOAP API that are not commonly found in public documentation.

What it needs

Requires brenda_client installed locally. About 8k tokens when loaded. Last updated 2026-08-07. 405 stars on the source repository.

What this skill does

BRENDA Database Overview BRENDA (BRaunschweig ENzyme DAtabase) is the world's most comprehensive enzyme information system, containing detailed enzyme data from scientific literature. Query kinetic parameters (Km, kcat), reaction equations, substrate specificities, organism information, and optimal conditions for enzymes using the official SOAP API. Access over 45,000 enzymes with millions of kinetic data points for biochemical research, metabolic engineering, and enzyme discovery. When to Use This Skill This skill should be used when: Searching for enzyme kinetic parameters (Km, kcat, Vmax) Retrieving reaction equations and stoichiometry Finding enzymes for specific substrates or reactions Comparing enzyme properties across different organisms Investigating optimal pH, temperature, and conditions Accessing enzyme inhibition and activation data Supporting metabolic pathway reconstruction and retrosynthesis Performing enzyme engineering and optimization studies Analyzing substrate specificity and cofactor requirements Core Capabilities 1. Kinetic Parameter Retrieval Access comprehensive kinetic data for enzymes: Get Km Values by EC Number: Parse Km Results: Extract Specific Information: 2. Reaction Information Retrieve reaction equations and details: Get Reactions by EC Number: Process Reaction Data: 3. Enzyme Discovery Find enzymes for specific biochemical transformations: Find Enzymes by Substrate: Find Enzymes by Product: Search by Reaction Pattern: 4. Organism-Specific Enzyme Data Compare enzyme properties across organisms: Get Enzyme Data for Multiple Organisms: Find Organisms with Specific Enzyme: 5. Environmental Parameters Access optimal conditions and environmental parameters: Get pH and Temperature Data: Cofactor Requirements: 6. Substrate Specificity Analyze enzyme substrate preferences: Get Substrate Specificity Data: Compare Substrate Preferences: 7. …

How to use it

Reference it in AdaL, Claude Code, Cursor or any coding agent — nothing to install:

@skills aiskillstore/brenda-database--0d2e15

View the source on GitHub

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